John C Mathers Selected Research

Carcinogenesis

1/2021	Author Correction: Age-associated mitochondrial DNA mutations cause metabolic remodeling that contributes to accelerated intestinal tumorigenesis.
10/2020	Age-associated mitochondrial DNA mutations cause metabolic remodelling that contributes to accelerated intestinal tumorigenesis.
10/2019	Obesity and bowel cancer: from molecular mechanisms to interventions.
1/2011	The CpG island methylation regulated expression of endothelial proangiogenic genes in response to β-carotene and arachidonic acid.
3/2008	Gender-specific modulation of tumorigenesis by folic acid supply in the Apc mouse during early neonatal life.
12/2007	Folate and colo-rectal cancer risk.
9/2004	Use of DNA from human stools to detect aberrant CpG island methylation of genes implicated in colorectal cancer.

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John C Mathers Research Topics

Disease

32	Neoplasms (Cancer) 12/2023 - 02/2003
26	Colorectal Neoplasms (Colorectal Cancer) 12/2023 - 02/2004
14	Obesity 12/2023 - 05/2006
11	Weight Loss (Weight Reduction) 02/2024 - 09/2009
11	Inflammation (Inflammations) 01/2022 - 10/2011
10	Body Weight (Weight, Body) 01/2024 - 05/2014
10	Overweight 12/2023 - 10/2015
9	Type 2 Diabetes Mellitus (MODY) 02/2024 - 11/2003
7	Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer) 01/2022 - 12/2008
7	Carcinogenesis 01/2021 - 09/2004
7	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 08/2011
6	Adenoma (Adenomas) 10/2020 - 02/2003
6	Polyps 12/2013 - 02/2003
5	Insulin Resistance 12/2022 - 06/2002
5	Colonic Neoplasms (Colon Cancer) 12/2013 - 06/2009
4	Dementia (Dementias) 01/2023 - 01/2018
3	Genetic Risk Score 01/2021 - 01/2017
3	Hypertension (High Blood Pressure) 10/2018 - 03/2014
2	Vitamin D Deficiency 12/2023 - 06/2018
2	COVID-19 02/2023 - 01/2020
2	Intestinal Failure 01/2023 - 01/2022
2	Frailty 01/2023 - 11/2022
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2022 - 05/2014
2	Non-alcoholic Fatty Liver Disease 01/2022 - 01/2015
2	Carcinoma (Carcinomatosis) 10/2020 - 12/2008
2	Sarcopenia 01/2020 - 12/2018
2	Genomic Instability 01/2020 - 01/2013
2	Malnutrition (Nutritional Deficiencies) 12/2018 - 01/2018
2	Metabolic Diseases (Metabolic Disease) 02/2016 - 02/2012
2	Mitochondrial Diseases (Mitochondrial Disease) 09/2014 - 01/2012
2	Rectal Neoplasms (Rectal Cancer) 12/2007 - 02/2003
2	Adenomatous Polyps 10/2007 - 07/2006
1	Chronic Disease (Chronic Diseases) 03/2024
1	Neural Tube Defects (Exencephaly) 02/2024
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2023
1	Virus Diseases (Viral Diseases) 01/2022
1	Fatty Liver 01/2022
1	Abdominal Obesity 01/2022
1	Arthritis (Polyarthritis) 12/2018

Drug/Important Bio-Agent (IBA)

20	Biomarkers (Surrogate Marker)IBA 03/2024 - 02/2004
14	Folic Acid (Vitamin M)FDA LinkGeneric 02/2024 - 10/2007
10	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2022 - 02/2003
10	Proteins (Proteins, Gene)FDA Link 08/2020 - 02/2003
8	Insulin (Novolin)FDA Link 02/2024 - 06/2002
8	NitratesIBA 01/2023 - 10/2015
8	Glucose (Dextrose)FDA LinkGeneric 12/2022 - 06/2002
8	Resistant StarchIBA 01/2022 - 02/2003
7	Mitochondrial DNA (mtDNA)IBA 01/2021 - 06/2009
6	DNA (Deoxyribonucleic Acid)IBA 12/2023 - 09/2004
6	CarbohydratesIBA 01/2021 - 09/2009
5	Vitamin D FDA LinkGeneric 12/2023 - 02/2013
4	Dietary Fiber FDA Link 01/2024 - 01/2017
4	SugarsIBA 03/2019 - 03/2008
4	Butyrates (Butyrate)IBA 01/2017 - 02/2003
4	Starch (Cornstarch)IBA 12/2012 - 02/2003
3	Antihypertensive Agents (Antihypertensives)IBA 02/2024 - 10/2018
3	MicroRNAs (MicroRNA)IBA 12/2022 - 01/2010
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 08/2011
3	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2020 - 07/2014
2	Hypoglycemic Agents (Hypoglycemics)IBA 02/2024 - 10/2018
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2023 - 11/2016
2	insulin receptor-related receptor (IRR)IBA 01/2022 - 12/2012
2	SolutionsIBA 01/2022 - 01/2020
2	Cholecalciferol (Vitamin D3)FDA Link 01/2022 - 06/2018
2	Blood Glucose (Blood Sugar)IBA 01/2021 - 01/2020
2	potassium nitrate (saltpeter)IBA 01/2020 - 11/2016
2	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 10/2018 - 09/2017
2	HomocysteineIBA 09/2017 - 01/2015
2	ApolipoproteinsIBA 09/2016 - 04/2012
2	CholesterolIBA 09/2016 - 01/2015
2	Fish OilsIBA 03/2016 - 08/2011
2	SeleniumIBA 01/2016 - 02/2013
2	Histones (Histone)IBA 09/2012 - 01/2010
2	Antineoplastic Agents (Antineoplastics)IBA 12/2011 - 01/2010
2	Protein Isoforms (Isoforms)IBA 11/2009 - 07/2006
1	Cell-Free Nucleic AcidsIBA 12/2023
1	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 12/2023
1	dimemorfan (AT 17)IBA 10/2023
1	Dihydrotachysterol (AT 10)IBA 02/2023
1	Indicators and Reagents (Reagents)IBA 11/2022
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2022
1	Ergocalciferols (Ergocalciferol)FDA LinkGeneric 01/2022
1	Alanine Transaminase (SGPT)IBA 01/2022
1	Interferon-gamma (Interferon, gamma)IBA 01/2022
1	Lipoproteins (Lipoprotein)IBA 01/2020
1	PlacebosIBA 01/2020
1	Retroelements (Retrotransposon)IBA 01/2020
1	Insulin-Like PeptidesIBA 10/2019
1	Dietary Plant Proteins (Vegetable Protein)IBA 03/2019
1	WD repeat containing planar cell polarity effectorIBA 01/2019

Therapy/Procedure

5	Bariatric Surgery 12/2023 - 10/2014
5	Mediterranean Diet 01/2023 - 10/2017
2	Therapeutics 01/2022 - 01/2018
2	Gastric Bypass (Roux-en-Y Gastric Bypass) 01/2018 - 10/2016
2	Plant-Based Diet 01/2018 - 05/2006
1	Enteral Nutrition (Feeding, Tube) 01/2023
1	Dentures 01/2023
1	Diet Therapy (Therapy, Diet) 01/2022
1	Home Parenteral Nutrition 01/2022
1	Glycemic Control 10/2018